Male Fertility is Declining Worldwide – Studies show


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Male Fertility is Declining Worldwide


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In the U.S., nearly 1 in 8 couples struggle with infertility. Unfortunately, physicians like me who specialize in reproductive medicine are unable to determine the cause of male infertility around 30% to 50% of the time. There is almost nothing more disheartening than telling a couple “I don’t know” or “There’s nothing I can do to help.”

Upon getting this news, couple after couple asks me questions that all follow a similar line of thinking. “What about his work, his cellphone, our laptops, all these plastics? Do you think they could have contributed to this?” What my patients are really asking me is a big question in male reproductive health: Does environmental toxicity contribute to male infertility?

Male Infertility

health fitness

health-and-stamina

Male fertility decline:

Infertility is defined as a couple’s inability to get pregnant for one year despite regular intercourse. When this is the case, doctors evaluate both partners to determine why.

For men, the cornerstone of the fertility evaluation is a semen analysis, and there are a number of ways to assess sperm. Sperm count – the total number of sperm a man produces – and sperm concentration – number of sperm per milliliter of semen – are common measures, but they aren’t the best predictors of fertility. A more accurate measure looks at the total motile sperm count, which evaluates the fraction of sperm that are able to swim and move.

In 1992, a study found a global 50% decline in sperm counts in men over the previous 60 years. Multiple studies over subsequent years confirmed that initial finding, including a 2017 paper showing a 50% to 60% decline in sperm concentration between 1973 and 2011 in men from around the world.

These studies, though necessary, focused on sperm concentration or total sperm count. So in 2019, a team of researchers decided to focus on the more powerful total motile sperm count. They found that the proportion of men with a normal total motile sperm count had declined by approximately 10% over the previous 16 years.

Environmental toxicity and reproduction

Scientists have known for years that, at least in animal models, environmental toxic exposure can alter the hormonal balance and throw off reproduction. Researchers can’t intentionally expose human patients to harmful compounds and measure outcomes, but we can try to assess associations.

As the downward trend in male fertility emerged, I and other researchers began looking more toward chemicals in the environment for answers. This approach doesn’t allow us to definitively establish which chemicals are causing the male fertility decline, but the weight of the evidence is growing.

A lot of this research focuses on endocrine disrupters, molecules that mimic the body’s hormones and throw off the fragile hormonal balance of reproduction. These include substances like phthalates – better known as plasticizers – and pesticides, herbicides, heavy metals, toxic gases, and other synthetic materials. source

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